Bleeding reduction after topical application of tranexamic acid together with Betadine solution in total knee arthroplasty. A randomised controlled study
نویسندگان
چکیده
منابع مشابه
Topical application of tranexamic acid reduces postoperative blood loss in total knee arthroplasty: a randomized, controlled trial.
BACKGROUND Topical application of tranexamic acid to bleeding wound surfaces reduces blood loss in patients undergoing some major surgeries, without systemic complications. The objective of the present trial was to assess the efficacy and safety of the topical application of tranexamic acid on postoperative blood loss in patients undergoing primary unilateral total knee arthroplasty with cement...
متن کاملIntraarticular Administration of Tranexamic Acid Following Total Knee Arthroplasty: A Case-control Study
Background: Tranexamic acid (TXA) has received extensive attention in management of blood loss in orthopedic surgeries. However, the ideal method of TXA administration is still controversial. This study aims to determine whether intraarticular injection of TXA reduces blood loss after total knee arthroplasty (TKA). Methods: Through a retrospective case-control study consecutive TKA patients...
متن کاملBlood Loss and Transfusion After Topical Tranexamic Acid Administration in Primary Total Knee Arthroplasty.
There has been much debate and controversy about the safety and efficacy of the topical use of tranexamic acid in primary total knee arthroplasty (TKA). The purpose of this study was to perform a meta-analysis to evaluate whether there is less blood loss and lower rates of transfusion after topical tranexamic acid administration in primary TKA. A systematic review of the electronic databases Pu...
متن کاملComparative study of topical vs. intravenous tranexamic acid regarding blood loss in total knee arthroplasty☆
OBJECTIVE To compare topical vs. intravenous tranexamic acid (TA) in total knee arthroplasty regarding blood loss and transfusion. METHODS Ninety patients were randomized to receive TA intravenously (20 mg/kg in 100 mL of saline; group IV), topically (1.5 g in 50 mL of saline, sprayed over the operated site, before release of the tourniquet; topical group), or intravenous saline (100 mL with ...
متن کاملTranexamic Acid and Total Knee Arthroplasty
Total knee arthroplasty (TKA) is one of the most commonly performed elective orthopaedic procedures in the United States [1]. By 2030, the number is estimated to grow by 673% to 3.48 million TKAs performed a year [1]. TKA provides significant pain relief and improvement in quality of life [2]. However TKA surgery is not without complications. Of note is the risk of bleeding and requirement for ...
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ژورنال
عنوان ژورنال: Orthopaedics & Traumatology: Surgery & Research
سال: 2015
ISSN: 1877-0568
DOI: 10.1016/j.otsr.2014.10.013